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Albireo completes A3309 phase 1b study in individuals with chronic idiopathic constipation Albireo today announced the completion of a stage 1b study showing a favorable tolerability and security profile of A3309 in sufferers with chronic idiopathic constipation. Furthermore, the info revealed appropriate efficacy indicators in this patient inhabitants. A3309 is an initial in class compound developed for the treatment of chronic idiopathic constipation and constipation-predominant Irritable Bowel Syndrome .