‘As brain tumor individuals begin living longer thanks to modern therapeutics, treatment-related unwanted effects become more important,’ Dr. Lawrence stated. ‘Traditional cancer trials have emphasized tumor control as a way to improve overall survival. Our study emphasizes the association of treatment unwanted effects with long-term outcomes. This novel finding is yet to be explained fully. The bottom line is that we need to be careful with patients who experience significant toxicity during treatment especially. Conversely, we can reassure those patients who’ve a smooth ride through radiation therapy they are more likely to do above average.’.. Acute neurological toxicity associated with chronic neurological toxicity in individuals with high-grade gliomas Patients with high-quality gliomas who experience acute neurological toxicity during their treatment were more likely to experience chronic neurological toxicity and shortened overall survival, according to researchers from the Kimmel Tumor Center in Jefferson.While this research couldn’t prove cause and effect, those boys who faced family complications during those early years were much more likely to have depressive disorder and anxiety at ages 7, 10 and 13, the researchers said. They also were more likely to have lower volume of a kind of tissue referred to as ‘gray matter’ in the mind by the time they reached ages 18 to 21. ‘The discovering that childhood experiences can affect the mind highlights early childhood not only as a period of vulnerability but also a period of opportunity,’ Barker’s group wrote.