Keith T. Flaherty, M Click to see more .D., Caroline Robert, M.D., Ph.D., Peter Hersey, M.D., Ph.D., Paul Nathan, M.D., Ph.D., Claus Garbe, M.D., Mohammed Milhem, M.B., Lev V. Demidov, M.D., Jessica C. Hassel, M.D., Piotr Rutkowski, M.D., Ph.D., Peter Mohr, M.D., Reinhard Dummer, M.D., Uwe Trefzer, M.D., James M.G. Larkin, M.D., Jochen Utikal, M.D., Brigitte Dreno, M.D., Marta Nyakas, M.D., Tag R. Middleton, Ph.D. Becker, M.D., Ph.D., Michelle Casey, Ph.D., Laurie J. Sherman, R.N., Frank S. Wu, M.D., Ph.D., Daniele Ouellet, Ph.D., Anne-Marie Martin, Ph.D., Kiran Patel, M.D., and Dirk Schadendorf, M.D. For the METRIC Study Group: Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma About 160,000 new cases of melanoma are diagnosed and 48,000 melanoma-related deaths occur worldwide every year.1 Among cancers in patients under 40 years, the incidence of melanoma is second only to that of breast cancer for leukemia and women for men.2 Before 2010, simply no systemic therapy have been proven to improve overall survival among patients with metastatic melanoma, and only modest improvements were observed with interferon as an adjuvant drug.7,8 The most commonly observed BRAF mutation, V600E, and the next most common, V600K, take into account 95 percent of the BRAF mutations within all patients with cancer.
The facility is the second such ‘house abroad’ building that is operated by the Seattle Cancer Care Alliance. Rooms are scheduled to be available to SCCA individuals by the finish of the month. The SCCA House will serve individuals visiting general oncology clinics and post-stem cell transplant sufferers returning for follow-up appointments. The properly monitored clean environment is designed for patients with some degree of immunosuppression. ‘This beautiful new facility can help fill a substantial demand for lodging for sufferers and their caregivers during several forms of cancer treatment, that may last so long as several weeks,’ said Norm Hubbard, SCCA executive vice president. Seattle Mayor Greg Nickels congratulated the SCCA for adding ‘world-course hospitality to world-class treatment.’ Local hotels have been the only various other selections for out-of-town patients apart from the 70-unit Pete Gross House, which serves primarily patients who are going through bone marrow and stem cell transplants at the SCCA.