Podoconiosis can be an important however neglected public and medical health burden in more than 10 countries across tropical Africa, Central and South America, and north India.1 It’s estimated that up to 1 1 million folks are affected by podoconiosis in Ethiopia alone.2,3 In the Wolaita zone of southern Ethiopia , it affects 1 in 20 people,2 imposes an immense economic burden,4 and causes severe public stigma.5 The World Health Organization recently designated podoconiosis as a neglected tropical disease in recognition of its impact ; unaffected people were recruited to serve as controls. All participants had been from the same wide geologic area included in reddish-brownish clay soils comprising colloid-size particles derived from volcanic basalt rocks.13 The genomewide association research was conducted by using samples from one randomly selected affected sibling from each family and an unaffected, unrelated control for every case patient.To fight the feelings of depression that often result from vision reduction, Dr. Rovner set out to help people that have macular degeneration through behavior activation. Quite simply, it’s a kind of psychological therapy that allows such patients to work with their visual limitations in order to become involved in actions they once participated in, than pull back from them and be disengaged rather. Developing and sticking to a coping plan can help convenience symptoms of depressive disorder To find if behavior activation could help ease their despair, 188 people, all with age-related macular degeneration and regarded at risk of clinical unhappiness, participated in his study. During the period of 8 weeks, a therapist came to their homes to work with the participants. Half of the people acquired a therapist talk to them about their eyesight while the other half had therapists who developed a coping technique .